- Born in 1451 in Genoa, an important trade and crusader port city
- Speculated that conversion of great Asian ruler would allow for conquering Middle East
- First saw a Muslim in real life as a teenager, but read about Islam before
- Described many of the native people in the New World in Muslim world terms
- On August 3, 1492, set sail from Spain to find all-water route to Asia
- Landed on an island in the Bahamas and explored Caribbean for next five months
- In letter, declares that found land could easily be conquered by Spain
- Gave gifts in an effort to win affection and convert the people to Christians